Antimicrobial and antioxidant potentials of non-cytotoxic extracts of corticolous lichens sampled in Armenia

Abstract Due to wide range of secondary metabolites, lichens were used from antiquity as sources colorants, perfumes and medicaments. This research focuses on exploring the antioxidant, antimicrobial cytotoxic activities methanol, ethanol, acetone extracts aqueous infusions corticolous sampled Armenia. Methanol, ethanol all tested active against Gram-positive bacterial strains. The most effective solvent retrieve compounds was methanol. Aqueous didn’t show any significant antibacterial antifungal activity. highest activity observed for methanol extract Ramalina sinensis . minimum inhibitory concentration 0.9–1.8 mg mL ? 1 Pseudevernia furfuracea demonstrated (Ø 12 mm). Methanol Parmelia sulcata largest 1,1-diphenyl-2-picryl-hydrazil (DPPH) radical scavenging (71 %). cytotoxicity measured human HeLa (cervical carcinoma) cell lines using microculture tetrazolium test assay. IC 50 values estimated Peltigera praetextata, Evernia prunastri, farinacea species in line within 1.8–2.8 considered non-cytotoxic. Obtained results suggest that studied can be prospective biotechnologies alternative antioxidant substances.